Inferior vena cava collapsibility index as a predictor of fluid responsiveness in sepsis-related acute circulatory failure

Abstract Background Assessing fluid responsiveness is the key to successful resuscitation of critically-ill sepsis patients. The use IVC variation favored among dynamic methods assessment in ICU because it non-invasive and inexpensive; moreover, does not demand a high level training. aim this study determine value respiratory variability for predicting spontaneously breathing patients with acute circulatory failure. Results In prospective observational study, fifty-eight admitted were enrolled after approval departmental Research Ethical Committee, informed written consent had been taken from Ultrasonographic echocardiographic parameters measured “IVC stroke volume (SV)” calculation inferior vena cava collapsibility index (IVCCI) cardiac output. These values obtained before (baseline) expansion bolus. showed that twenty-nine (50%) considered be responders, an increase CO by 10% or more challenge. There was significant difference between responders non-responders baseline IVCCI ( p < 0.001). no differences terms demographic clinical characteristics. Also, there statistically significantly larger maximum (IVC max) minimum min) diameters than 0.037 0.001 respectively. suggested cut off regarding predict response infusion 0.32 chance above figure (a sensitivity 72.41% specificity 82.76%). Conclusions Inferior can sensitive good predictor responsiveness, being based on safe technique compared other such as central venous pressure (CVP) measurement pulmonary artery catheter insertion.